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Wednesday, 10 March 2010
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RNAi — Gene Function Revealed by RNA Interference

RNA interference (RNAi) has become the tool of choice for studying gene function by sequence-specific gene silencing in the presence of double stranded RNA (dsRNA) in the cell.

ImaGenes and Sigma-Aldrich have formed a cooperation to provide leading RNAi tools for gene silencing including siRNA and shRNA resources.

MISSION®shRNA tools were developed within the efforts of The RNAi Consortium (TRC) to generate genome-scale libraries based on a vector that allows transfection and transduction of a broad range of target cells.

Pre-designed MISSION®siRNAs were established in an exclusive partnership with Rosetta Inpharmatics, using a proprietary and highly innovative design algorithm ensuring a most effective and specific knockdown of the targeted gene.


 

Available Products

Category Type Applications
shRNA plasmid short/long term gene silencing
lentiviral particle long term gene silencing for cells which are difficult to transfect
siRNA RNA duplex molecule short term gene silencing


Gene Silencing by RNAi — The Basics

Gene-based Search for MISSION™ siRNA and shRNAs  
 
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  Contact


Tel: +49 30 9489 2444


Tel: +49 30 9489 2462

Fax: +49 30 9489 2449



 Downloads & More
pdf-File - (418kB)
RNAi Resource Flyer
 

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