aCGH technology measures DNA copy number differences between a reference genome and your sample genome. It provides the highest level resolution for detecting a wide range of copy number changes on either a genome-wide or fine-tiling level, including:
- Homozygous and hemizygous deletions
- Single and multiple copy amplifications
- Unbalanced translocations
Key features and benefits of imaGenes' aCGH Service:
- Broad range of available array formats for whole genome or chromosome-specific surveys.
- Tailored fine-tiling aCGH arrays for breakpoints at ultrahigh resolution in DNA targets located in any subset of genomic regions
- Tunable resolution: 50kb - 100bp
- High sample throughput by multiplex formats for detecting larger aberrations on whole genome level, or targeting only narrow regions of interest.
- Delivered segmentation data can be easily visually interpreted with SignalMap™ software (see Figure)
- Quick turnaround from samples to data: data are typically delivered 3-4 weeks after samples passed our incoming quality control if arrays are in stock
- References
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